>>107021754At the time when Hal got his powers by accident, Megamind hadn't decided yet who exactly should be getting the superpowers of Titan. He knew what kind of character qualities he was after, but he hadn't thought about where he would find the kind of person he wanted, and he didn't have any candidates in mind yet.
However, the dialogue was making strong hints that if he'd had more time to think about it and if he had been able to actually choose the person who would become his nemesis, it's very likely he would've chosen Roxanne.