That's Ultimate Marvel. In issue #6 of the first 'Ultimates' series, Janet and Hank get in a fight (It had been revealed that Hank is structurally physically abusive on a much more serious scale than in the 616 universe); he takes her to task for being a mutant, she says he is not half the scientist Bruce Banner is and then he hits her, she shrinks down and zaps him and then he sprays her with bug spray and lets his ants loose on her.
She doesn't die, but Hank goes on the run; Cap hunts him down and beats the shit out of him, even when he takes giant form.
Hank's on probation from then on, he builds a bunch of robots to try to ingratiate himself with SHIELD again but gets rebuffed, then he throws in with the invaders from 'Ultimates 2', then turns on them when it looks like they are losing; he's let back on the team, gets replaced by Ultron for a bit, then finally sacrifices himself to save the team fron exploding Multiple Men after Janet is killed and her corpse eaten by the Blob.
The Ultimate Universe started off well but goddamn, it did not END well. Although the middle was the worst.