While I enjoy "Night in the Woods" and other works with a similar cutesy art style, I find that MM&O resonates with me a lot more. I think part of that is the gross and unappealing manner in which Simon Hanselmann presents the lives of the comic's titular characters. He doesn't try to cutesify or soften anything about how Megg, Mogg, Owl, and Werewolf Jones act. They're bad, ugly people who do bad, ugly things to one another.
If MM&O was done by another artists, I could see Werewolf Jones being presented as being gruff but having a heart of gold. I like that Hanselmann never does anything like that or tries to make him sympathetic. He's just a repulsive monster who feels no remorse for anything he does.