Not him, but technically no. However, rejection and the idea of losing someone you love are both classic tropes in most NTR/cuckolding ficition, even if neither are together but one is pining for the other. Jealousy and the loss of your love are mainstays of NTR, usually ending with the destruction of whatever relationship was had.
Cuckolding, on the other hand, tends to be between an actually established couple with permission of infedelity between one or both parties. The relationship is expected to survive, if not propsper between the cuck and his partner because of this. Though cases of "cuckold regret" do pop up in the more depressing stories.