Risus campaign that started as a one-shot "awakened animals with superpowers" joke while we were drunk and bored, got more than a few sessions out of it.
GM had us take three pools: Animal, Superpower(rando'd off of the superpower wiki, or suggested so long as it wasn't too asinine or OP), and Intelligence level(rolled at random).
GM thought I'd just use it to make myself a bigger octo from time to time and probably eat half of Manhattan out of boredom.
I played Tako(yaki), the Iron Tentacle, used density Manipulation on the ends of my tentacles to apply a fuckton of kinetic force to my slaps, and was the usual face of the party, when Ceviche (a chihuaha with Telepathy who only 'spoke' and understood Spanish and Latin because he was the pet of a Padre in Spanish Harlem)
Played him as a stand up guy, just doing the right thing.
He did have to avoid Chinatown and such, as rumors of his flesh providing superpowers to those that consumed it and just general tentacle fetishists
We also lost Jersey to a demon invasion. But that was Mittens' fault.