I run a game for a party of dexfags with one strength-based fighter. For some reason, the dexlets continually choose brute force options (kicking down doors, grappling, scaling walls, swimming against tides) then complain when I won't let them roll Dex instead of Str. No, twiggy, you can't roll Acrobatics to "jump up" a sheer cliff face.
Anyway, yeah. Being the only strong guy will come in plenty useful, but you might want to keep your distance when it's time to be stealthy.