I don't really think that it's like that. Like I have schyzophrenia with signs of autism, if I imagine graph with "synaptic prunning" too little and too much, I should be normal?
Like there is neuroplasticity, and you can get important neuron connections transformed to do some job that comes from missrepresented pattern. I think that's the case in both of this disseases.
Howevery synaptic loops are redundant and still capable for learning, modern schyzo pills reduce neuroplasticity, but that keeps you in certain state of mind you don't want to be in.
I would try to attempt eliminating this disseases by serotogenic stuff with induced neurogenesis and plasticity, forming a normal reaction.
Normal reaction to enviroment can't ever be formed in mental hospital.