Wait, no, I think there's something here. God creates Adam from clay, Clayface creates Annie; Adam disobeys God by eating the forbidden fruit - Annie disobeys Clayface -
What would be her forbidden fruit? Tim? Love? Just even basic genuine friendship?
God, angered casts Adam out; Clayface, angered casts Annie out - or maybe there's juxtaposition here, in Annie having to fight to be allowed to be cast out - to be her own person and be deprived of (clay) life.
Depending on how one writes the relationship between Clayface and Annie - maybe start them out sort of hivemindesque, or have being part of Clayface sort of comforting (like being "home"?), the separation could be written as bittersweet, albeit a good end. Alternatively, keep with the juxtaposition and have it be just straight happy.
Dammit, I don't need these ideas. I have video game fanfic I'm overdue on writing already.