They fear 4 because they know 4-chan means their girl will lose.
Ninofags were saying nino was lolikano too. Now they know it's 4-chan. They feel threatened by her because she's best girl, the promised girl, the true heroine, and soon to be the bride.
Nino has pulled out all the stops. Tsun, dere, drugging, confessions, jumping into baths and offering massages like a thot, etc only to get few flowers in the background. Only to have 4-chan do the same with 0 effort.
The absolute state of 2fags right now is still in denial, but soon they'll be crying along with their 2fu.