It seems you people don't quite understand how powerful El Hermano has become.
At this point, even the King of all couldn't touch him unless he had Reader-level (class 2) - or possibly even Author-level (class 1) knowledge of El Hermano and his powers. As even Toriyama is surprised by El Hermano at times, only El Grande Abuelo (with class 0 knowledge AKA omniscience) could win for sure. And El Grande Abuelo isn't real.
Cut off his head? He'll use Namekian ki to regenerate his body.
Destroy his heart? He'll use Boo ki to reanimate.
Incinerate him? His soul will stick the atoms back together.
And every time you kill him... he comes back stronger than before thanks to saiyan heritage.
El Hermano is a waking nightmare. He will be considered the King of King of all, and the first to originate from the mortal world.